Evolence is a dermal filler that is injected under the skin to fill out medium to deep facial wrinkles. A good example of the kinds of lines Evolence treats particularly well are the lines from the nose to the corners of the mouth, also known as nasolabial folds. Because Evolence is a thicker gel than many other dermal fillers, it more efficiently treats these deeper lines and wrinkles.
History of Evolence: 2004-2008
Derived from porcine collagen, specifically tendons, Evolence was introduced in 2004 in Italy at the annual meeting of the European Academy of Dermatology and Venereology. In 2005, it was approved for use in the UK, but it was not until 2008 that the FDA finally approved Evolence for treating facial wrinkles in the United States. Its unique, collagen-based structure has led cosmetic surgeons to develop additional uses for Evolence, as well.
2008 and Beyond
In 2009, the FDA approved Evolence to be labeled as effective for up to one year. It was the first dermal filler to be approved to make these claims of long-term effects. But in November of that same year, Johnson and Johnson announced they were discontinuing manufacture of Evolence due to low sales figures. Existing supplies will remain guaranteed by the company.