JUVEDERM ® is a filler injection of hyaluronic acid into the facial tissue. Hyaluronic acid is a naturally occurring substance found in the skin and muscles. Cosmetic or dermatological surgeons perform the injections in order to reduce moderate to severe wrinkles on the face. Deep folds can also be softened with JUVEDERM ® .?
History of JUVEDERM ® ?
Two medical researchers at Columbia University originally determined two of the functions of hyaluronic acid to be hydration of the skin and sustaining a plump appearance. In 1934, these researchers, Karl Meyer and John Palmer, gave this substance its name from the combination of the Greek word, hyalos, meaning glass, and the uronic sugar within the substance. Hyaluronic acid was later used for baking in the 1940s. Its medicinal use did not come about until the 1990s when uses started to include relief for joint pain and wound treatment. The first uses of hyaluronic acid for facial treatments took place in Europe in 1996.?
In this century, hyaluronic acid has become a chief ingredient in skin treatments. JUVEDERM ® makes use of this substance through a process which creates a gel that can last longer than the liquid form after injection, for better lasting results. Clinical trials were conducted to evaluate safety and efficacy before the product was approved for use in the United States by the FDA in 2006. Two forms are available: the injectable gel and an ultra plus version for more volume.