Potential Risks and Complications of Radiesse

Radiesse is a dermal filler which is injected into the skin to relieve wrinkle lines and other facial folds. It contains microspheres of calcium hydroxylapatite, which are suspended in water based gel. Radiesse produces results which last for nearly two years, after which repeat treatments will be required to maintain the results.

Since Radiesse consists of ingredients which occur in the body naturally, there is a very low risk of an allergic reaction to the injection. You do not even need to get a sensitivity test done before undergoing the treatment. There are no known, serious side effects associated with Radiesse, though minor risks may occur:

Pain or Discomfort

Even though the injection involves small doses and most people do not feel any pain, you might experience minor pain or discomfort during and after the procedure. A topical anesthetic can be used to relieve pain during the procedure, and pain medication can be taken for pain after the procedure. In case of increased pain which is continuing for several hours, you should consult your physician immediately.

Bruising and Swelling

Like any injection–related procedure, Radiesse might also cause slight bruising and swelling after the procedure. Avoid the intake of alcohol and aspirin before and after the procedure to minimize this risk. Also, avoid exposing the injected area to the sun or applying makeup on it for a couple of days after the procedure.


If you are prone to developing certain scars, such as keloids or hypertrophic scars, then this could result in hard nodules of scar tissue, which would then turn red or pink. This is extremely undesired for the face and can lead to permanent scarring. In such cases, it is best to consult your physician before undergoing the treatment.

Hard Nodule Formation

Radiesse is not suitable for thin–skinned areas, as there is a small risk of the injected material forming hard nodules under the skin. This is the reason why manufacturers of Radiesse advise against using Radiesse for lip augmentation. Once such nodules are formed, they will have to be surgically removed, or result in the need for insistent use of steroid medication to break up the nodules.

Tenderness at Injected Site

The injected area will feel tender and might appear a little discolored for a few hours after the treatment. You might also experience some itching at the site. All of this should resolve within a few days of the treatment. In case it does not, consult your doctor immediately.

Some other rare complications or risks associated with Radiesse include infections or allergic reactions. In some cases, calcium deposits have been known to rise up to the surface of the skin, but in such cases, these deposits can be easily removed. To avoid any serious risks, make sure that you undergo the treatment with a medical doctor, preferably a plastic or cosmetic doctor. The more experienced they are, the better. 

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